Efficient Elimination of Inhaled Nanoparticles from the Alveolar Region: Evidence for Interstitial Uptake and Subsequent Re-entrainment onto Airways Epithelia

February 8th, 2007

“We conclude that NP are much less phagocytized by AM than large particles but are effectively removed from the lung surface towards the interstitium. Even from these interstitial sites they undergo AM-mediated long-term NP clearance to the larynx.”

Efficient Elimination of Inhaled Nanoparticles from the Alveolar Region: Evidence for Interstitial Uptake and Subsequent Re-entrainment onto Airways Epithelia
Semmler-Behnke M, Takenaka S, Fertsch S, Wenk A, Seitz J, Mayer P, Oberdorster G, Kreyling WG. 2007. Environ Health Perspect: doi:10.1289/ehp.9685. [Online 6 February 2007]

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