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	<title>toxportal</title>
	<link>http://www.toxportal.com</link>
	<description>In the land of the blind the one-eyed man is king...</description>
	<pubDate>Fri, 20 Jun 2008 15:47:59 +0000</pubDate>
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	<language>en</language>
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		<title>Up-REACH!</title>
		<link>http://www.toxportal.com/2008/06/17/147/</link>
		<comments>http://www.toxportal.com/2008/06/17/147/#comments</comments>
		<pubDate>Tue, 17 Jun 2008 22:14:48 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
	<category>Chemical Regulations</category>
	<category>Conceptual Toxicology</category>
	<category>Tools</category>
	<category>Coding</category>
	<category>Datasets</category>
		<guid isPermaLink="false">http://www.toxportal.com/2008/06/17/147/</guid>
		<description><![CDATA[
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			<content:encoded><![CDATA[<form name="qs_search_form" onsubmit="return check(this)" action="http://www.stimulus-response.net/reach/superlist_search.php" method="post">
<p align="left"><script>  function getURLParam(strParamName){  var strReturn = &#8220;&#8221;;  var strHref = window.location.href;  if ( strHref.indexOf(&#8221;?&#8221;) > -1 ){    var strQueryString = strHref.substr(strHref.indexOf(&#8221;?&#8221;)).toLowerCase();    var aQueryString = strQueryString.split(&#8221;&amp;amp;amp;amp;amp;&#8221;);    for ( var iParam = 0; iParam < aQueryString.length; iParam++ ){      if (  	aQueryString[iParam].indexOf(strParamName + "=") > -1 ){        var aParam = aQueryString[iParam].split(&#8221;=&#8221;);        strReturn = aParam[1];        break;      }    }  }  return strReturn;  }  </script><strong>CAS number</strong>  <input maxlength="25" size="12" name="search_fd6" type="text" />   <input type="submit" name="QS_Submit" value="Search" />  <input type="hidden" name="act" value="n" /><input type="hidden" name="multisearch_fd6" /></p>
<p align="left">If you regularly search for information about chemicals, then you may want to try my new tool, Up-REACH! (with apologies for the name..). The tools provides meta-links for 105,000 chemical entries drawn from the EU registration lists (EINECS / ELINCS).</p>
<p align="left">I built Up-REACH to allow rapid access to key chemtox information databases (chemIPplus / PubChem), Phys-Chem (NIST), literature (Hubmed), and EU Classification (ESIS). It&#8217;s a good jumping-off point for a chemical hazard assessment, and greatly facilitates read-across assesments.  It has saved me a lot of time and mouse-clicks.</p>
<p align="left">You are very welcome to use it. The main search interface, with a few more options, can be found <a href="http://www.stimulus-response.net/reach/superlist_search.php?" target="_blank">here</a>.</p>
<p align="left"><strong>Where is the Risk Inventor</strong><strong>y Tool?</strong></p>
<p align="left">I stopped development of the Risk Inventory Tool some time ago. Although the concepts are very relevant to the exposure work required for REACH, there are software providers currently spending time, and our money, to develop REACH-ready implementations.</p>
<p>Good luck to them! <img src='http://www.toxportal.com/wp-includes/images/smilies/icon_smile.gif' alt=':-)' class='wp-smiley' /><br />
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		<item>
		<title>REACH: RIP 3.2 Guidance</title>
		<link>http://www.toxportal.com/2008/06/17/reach-rip-32-guidance/</link>
		<comments>http://www.toxportal.com/2008/06/17/reach-rip-32-guidance/#comments</comments>
		<pubDate>Tue, 17 Jun 2008 22:01:10 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
	<category>Chemical Regulations</category>
	<category>Environmental Health</category>
		<guid isPermaLink="false">http://www.toxportal.com/2008/06/17/reach-rip-32-guidance/</guid>
		<description><![CDATA[Here it is, the hefty Guidance on Information Requirements and Chemical Safety Assessment.
The purpose of the concise guidance is to support the processes needed to meet the information requirements on intrinsic properties of substances to be registered, and where relevant to carry out a chemicals safety assessment.


]]></description>
			<content:encoded><![CDATA[<p><a title="RIP3.2" href="http://reach.jrc.it/docs/guidance_document/information_requirements_en.htm" target="_blank">Here it is</a>, the hefty Guidance on Information Requirements and Chemical Safety Assessment.</p>
<p><em>The purpose of the <strong>concise</strong> guidance is to <strong>support the processes</strong> needed to meet the information requirements on intrinsic properties of substances to be registered, and where relevant to carry out a chemicals safety assessment.</em></p>
<p><img src="http://reach.jrc.it/images/concise.jpg" />
</p>
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		<title>A viable alternative</title>
		<link>http://www.toxportal.com/2007/08/06/a-viable-alternative/</link>
		<comments>http://www.toxportal.com/2007/08/06/a-viable-alternative/#comments</comments>
		<pubDate>Mon, 06 Aug 2007 18:05:09 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
	<category>General</category>
		<guid isPermaLink="false">http://www.toxportal.com/2007/08/06/a-viable-alternative/</guid>
		<description><![CDATA[A viable alternative
Railing against &#8216; tick-box&#8217; toxicology&#8230;

]]></description>
			<content:encoded><![CDATA[<p><a href="http://www.rsc.org/chemistryworld/News/2007/July/24070701.asp">A viable alternative</a><br />
Railing against &#8216; tick-box&#8217; toxicology&#8230;
</p>
]]></content:encoded>
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		<item>
		<title>Efficient Elimination of Inhaled Nanoparticles from the Alveolar Region: Evidence for Interstitial Uptake and Subsequent Re-entrainment onto Airways Epithelia</title>
		<link>http://www.toxportal.com/2007/02/08/efficient-elimination-of-inhaled-nanoparticles-from-the-alveolar-region-evidence-for-interstitial-uptake-and-subsequent-re-entrainment-onto-airways-epithelia-2/</link>
		<comments>http://www.toxportal.com/2007/02/08/efficient-elimination-of-inhaled-nanoparticles-from-the-alveolar-region-evidence-for-interstitial-uptake-and-subsequent-re-entrainment-onto-airways-epithelia-2/#comments</comments>
		<pubDate>Thu, 08 Feb 2007 12:53:46 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
	<category>Nanotechnology</category>
	<category>Occupational Health</category>
		<guid isPermaLink="false">http://www.toxportal.com/2007/02/08/efficient-elimination-of-inhaled-nanoparticles-from-the-alveolar-region-evidence-for-interstitial-uptake-and-subsequent-re-entrainment-onto-airways-epithelia-2/</guid>
		<description><![CDATA[&#8220;We conclude that NP are much less phagocytized by AM than large particles but are effectively removed from the lung surface towards the interstitium. Even from these interstitial sites they undergo AM-mediated long-term NP clearance to the larynx.&#8221;
Efficient Elimination of Inhaled Nanoparticles from the Alveolar Region: Evidence for Interstitial Uptake and Subsequent Re-entrainment onto Airways [...]]]></description>
			<content:encoded><![CDATA[<p><em>&#8220;We conclude that NP are much less phagocytized by AM than large particles but are effectively removed from the lung surface towards the interstitium. Even from these interstitial sites they undergo AM-mediated long-term NP clearance to the larynx.&#8221;</em></p>
<p><a href="http://feeds.feedburner.com/~r/ehpinpress/~3/87370089/abstract.html">Efficient Elimination of Inhaled Nanoparticles from the Alveolar Region: Evidence for Interstitial Uptake and Subsequent Re-entrainment onto Airways Epithelia</a><br />
Semmler-Behnke M, Takenaka S, Fertsch S, Wenk A, Seitz J, Mayer P, Oberdorster G, Kreyling WG. 2007. <em>Environ Health Perspect</em>: doi:10.1289/ehp.9685. [Online 6 February 2007]
</p>
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		<item>
		<title>GrantsNet: International Funding Index 2007</title>
		<link>http://www.toxportal.com/2007/02/08/grantsnet-international-funding-index-2007/</link>
		<comments>http://www.toxportal.com/2007/02/08/grantsnet-international-funding-index-2007/#comments</comments>
		<pubDate>Thu, 08 Feb 2007 08:56:20 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
	<category>General</category>
		<guid isPermaLink="false">http://www.toxportal.com/2007/02/08/grantsnet-international-funding-index-2007/</guid>
		<description><![CDATA[In case you were curious&#8230;.
GrantsNet: International Funding Index
The International Grants and Fellowships Index offers the latest listing of funding opportunities from Europe, Asia, and the Americas.

]]></description>
			<content:encoded><![CDATA[<p>In case you were curious&#8230;.
<p><a href="http://sciencecareers.sciencemag.org/career_development/previous_issues/articles/2005_11_04/grantsnet_international_funding_index">GrantsNet: International Funding Index</a><br />
The International Grants and Fellowships Index offers the latest listing of funding opportunities from Europe, Asia, and the Americas.
</p>
]]></content:encoded>
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		<item>
		<title>JabRef: an Open Source Reference manager</title>
		<link>http://www.toxportal.com/2007/02/07/jabref-open-source-reference-manager/</link>
		<comments>http://www.toxportal.com/2007/02/07/jabref-open-source-reference-manager/#comments</comments>
		<pubDate>Wed, 07 Feb 2007 09:38:17 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
	<category>Tools</category>
	<category>Datasets</category>
		<guid isPermaLink="false">http://www.toxportal.com/2007/02/07/jabref-open-source-reference-manager/</guid>
		<description><![CDATA[Despite my initial enthusiasm for Connotea (see below) I quickly found that, whilst various popular import and export formats are supported, it does not allow you to export as .rtf reference list. This is a function that I&#8217;m sure most researchers would like, as a way to save on the drudgery of typing-in all those citations, [...]]]></description>
			<content:encoded><![CDATA[<p>Despite my initial enthusiasm for Connotea (see below) I quickly found that, whilst various popular import and export formats are supported, it does not allow you to export as .rtf reference list. This is a function that I&#8217;m sure most researchers would like, as a way to save on the drudgery of typing-in all those citations, nicely formatted.</p>
<p>I can see all you <a href="http://www.endnote.com/" target="_blank">endnote</a> users smiling smugly right now. But not everyone want to pay $299 for a reference manager <img src='http://www.toxportal.com/wp-includes/images/smilies/icon_razz.gif' alt=':-P' class='wp-smiley' /> </p>
<p>With so many resourceful and generous open-source developers out there, a quick scan of <a href="http://sourceforge.net/" target="_blank">Sourceforge</a> revealed <a href="http://jabref.sourceforge.net/" target="_blank">JabRef, a free Java-based reference manager</a> with some very nice features, including a solution for the aforementioned formatting malaise, and the ability to import/export in other popular formats. <a href="http://www.regular-expressions.info/" target="_blank">Regular expressions</a> are supported!</p>
<p>JabRef works perfectly at home, but there is no access to Medline through the proxy server at work (!?). So, Connotea stays in my favourites list for now, feeding JabRef with all that information.</p>
<p>Another score for efficiency and a tip of the hat to the Open Source community.
</p>
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		<title>&#8220;Seemingly realistic results can be achieved without much intellectual effort.&#8221;</title>
		<link>http://www.toxportal.com/2007/02/02/seemingly-realistic-results-can-be-achieved-without-much-intellectual-effort/</link>
		<comments>http://www.toxportal.com/2007/02/02/seemingly-realistic-results-can-be-achieved-without-much-intellectual-effort/#comments</comments>
		<pubDate>Fri, 02 Feb 2007 18:26:42 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
	<category>General</category>
	<category>Reality Bites</category>
		<guid isPermaLink="false">http://www.toxportal.com/2007/02/02/seemingly-realistic-results-can-be-achieved-without-much-intellectual-effort/</guid>
		<description><![CDATA[Here's a recipe for a REAL 'Global Warmer, a fond memory from the bartender days...

Into a cocktail shaker with lots of ice:

1 measure Gin
1 measure Vodka
1/2 measure Peach Schnapps

Top-up with pineapple Juice and shake. Delicious!

Enjoy whilst watching media carnival. ]]></description>
			<content:encoded><![CDATA[<p>A revealing article by Hendrik Tennekes, retired Director of Research, Royal Netherlands Meteorological Institute, gives a cold-eye view relevant to <a href="http://www.junkscience.com/" target="_blank">today&#8217;s IPPC firm pronouncement</a> of guilt on human activities as the major cause of global warming. </p>
<p><a href="http://climatesci.colorado.edu/2007/01/31/a-personal-call-for-modesty-integrity-and-balance-by-henkrik-tennekes/" target="_blank">A Personal Call For Modesty, Integrity, and Balance by Hendrik Tennekes</a>
</p>
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		<item>
		<title>Connotea: free online bibliographic tool</title>
		<link>http://www.toxportal.com/2007/02/02/connotea-free-online-bibiographic-tool/</link>
		<comments>http://www.toxportal.com/2007/02/02/connotea-free-online-bibiographic-tool/#comments</comments>
		<pubDate>Fri, 02 Feb 2007 15:35:28 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
	<category>Tools</category>
	<category>Datasets</category>
		<guid isPermaLink="false">http://www.toxportal.com/2007/02/02/connotea-free-online-bibiographic-tool/</guid>
		<description><![CDATA[For anyone tired of being confined to endnote to collect  references, a mobile solution is at hand! Today I came across an elegant and free web2.0 solution called Connotea:
http://www.connotea.org/
Quite easy to set-up, it allows you to painlessly store, manage and share bibliographic references and, to enter multiple tags for each reference. This means you can strip out the references to any [...]]]></description>
			<content:encoded><![CDATA[<p>For anyone tired of being confined to <a href="http://www.endnote.com/" target="_blank">endnote</a> to collect  references, a mobile solution is at hand! Today I came across an elegant and free web2.0 solution called Connotea:</p>
<p><a href="http://www.connotea.org/">http://www.connotea.org/</a></p>
<p>Quite easy to set-up, it allows you to painlessly store, manage and share bibliographic references and, to enter multiple tags for each reference. This means you can strip out the references to any RSS reader or other formats - fantastic!</p>
<p>Using a copy of equally wonderful <a href="http://www.curiostudio.com/" target="_blank">GreatNews RSS reader</a> on a usb stick, your valuable bibliographic hoard is in your pocket.
</p>
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		<item>
		<title>Wallstrom: REACH, Climate Change</title>
		<link>http://www.toxportal.com/2007/02/01/wallstrom-watch-reach-climate-change/</link>
		<comments>http://www.toxportal.com/2007/02/01/wallstrom-watch-reach-climate-change/#comments</comments>
		<pubDate>Thu, 01 Feb 2007 11:54:48 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
	<category>Chemical Regulations</category>
		<guid isPermaLink="false">http://www.toxportal.com/2007/02/01/wallstrom-watch-reach-climate-change/</guid>
		<description><![CDATA[REACH, Climate Change
&#8220;I cannot hide the feeling that the proposal could have been more far-reaching and that I would have wanted to see a more ambitious chemicals management‘s regulation. Despite the shortcomings of the new emerging text on REACH, the two main goals (abolishment of current dual system for the risk assessment of chemicals and [...]]]></description>
			<content:encoded><![CDATA[<p><a href="http://blogs.ec.europa.eu/blog_wallstrom/page/wallstrom?entry=reach_climate_change">REACH, Climate Change</a></p>
<p><em>&#8220;I cannot hide the feeling that the proposal could have been more far-reaching and that I would have wanted to see a more ambitious chemicals management‘s regulation. Despite the shortcomings of the new emerging text on <span class="caps">REACH</span>, the two main goals (abolishment of current dual system for the risk assessment of chemicals and the burden of proof) of <span class="caps">REACH</span> still hold. And it is better to have a law that a draft law!&#8221;</em><em> </em></p>
<p><em>&#8220;It will be interesting to see who will be the first producer who would provide the full safety file to the Chemicals agency….&#8221; </em></p>
<p>I would be more worried about whether the shiny new <a title="See the beautiful views!" href="http://www.hel.fi/wps/portal/Helsinki_en/echa?WCM_GLOBAL_CONTEXT=/en/Helsinki/echa" target="_blank">European Chemicals Agency</a> will have the capacity!
</p>
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		<title>Experts tell EU to prop up ethics in nanomedicine</title>
		<link>http://www.toxportal.com/2007/02/01/experts-tell-eu-to-prop-up-ethics-in-nanomedicine/</link>
		<comments>http://www.toxportal.com/2007/02/01/experts-tell-eu-to-prop-up-ethics-in-nanomedicine/#comments</comments>
		<pubDate>Thu, 01 Feb 2007 11:51:58 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
	<category>Nanotechnology</category>
		<guid isPermaLink="false">http://www.toxportal.com/2007/02/01/experts-tell-eu-to-prop-up-ethics-in-nanomedicine/</guid>
		<description><![CDATA[Experts tell EU to prop up ethics in nanomedicine
Nanotechnologies can open up promising areas in diagnosis and treatment but measures are needed to ensure that related medical products and devices are safe, scientific experts told the Commission.

]]></description>
			<content:encoded><![CDATA[<p><a href="http://www.euractiv.com/en/science//article-161222" target="_blank">Experts tell EU to prop up ethics in nanomedicine</a><br />
Nanotechnologies can open up promising areas in diagnosis and treatment but measures are needed to ensure that related medical products and devices are safe, scientific experts told the Commission.
</p>
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