Ultimate Carcinogenic Metabolites from Aromatic and Heterocyclic Aromatic Amines: A Computational Study in Relation to Their Mutagenic Potency
Gabriela L. Borosky
Web Release Date: Tue, 30 Jan 2007 00:00:00 EST (Article) DOI: 10.1021/tx600278q
Details here:
A good day for…. unscrupulous public health pundits, consultant toxicologists (hihi), the box-ticking mentality, mindless socialism.
A bad day for… about 9 million animals who will be intentionally and needlessly poisoned, scientific reason, Europe’s credibility.
Green emerges triumphant over industry in latest REACH wrangle
Mmmm, not much to be triumphant about really….
The EU Parliament must maintain it’s credibility in the face of the potential damage to European competitiveness, and the pressure to ratify this legislation by the end of the year. Voting for the increased restrictions, the Sacconi Proposals, means concilliation, and that means another delay in implementation.
They’ve surely copped-it by now that, what in spirit is a very worthy piece of legislation, has become corrupted into an expensive eurocratic papermill. Ultimately, we stifle innovation, and logically derived risk management, through the smokescreen of hazard-based precaution.
These proposals are simply unworkable.
Meanwhile, the inherent contradiction of the REACH legislation - a significant increase in enforced and unnecessary animal testing without decisive action on the mandated drive to reduce such testing - remains yet another embarrassing pimple for the EU ‘pro-ject’.
What could have been a model for a workable risk-based, and thus far more effective, system has been reduced to a slanging match with pitiful displays of triumphalism.
A ‘Hall of Shame’ is sure to follow….
There is a very nice, informative poster issued by APPE which they have turned into an interactive flash presentation. If you have ever doubted the ubiquity of petrochemicals in day-to-day life, then this will be a real eye-opener.
Have a look at: www.petrochemistry.net/flowchart
Future of Toxicology-Predictive Toxicology: An Expanded View of “Chemical Toxicity”
Ann M. Richard
Web Release Date: Sat, 2 Sep 2006 EDT (Article) DOI: 10.1021/tx060116u
Classification and labelling of chemicals
The European Commission has launched an Internet Consultation on a proposed Regulation on the Classification and Labelling of chemicals based on the United Nations Globally Harmonised System (GHS).
Chemicals Policy review (REACH)
On 29 October 2003, the Commission presented its proposals for a complete and radical review of the EU’s chemical substances policy. The proposal sets up a comprehensive system for the registration, evaluation, authorisation of chemicals (REACH). It still needs to be approved by the Council and the European Parliament.
Asthmagen? Critical assessments of the evidence for agents implicated in occupational asthma
This compendium originally comprised 32 such assessments when it was published in 1997, reported in a standard format and arranged alphabetically by common name. A further 12 assessments were added with publication of a Supplement in 1998. The 2001 Supplement comprises an additional 16 assessments.
Tiny inhaled particles take easy route from nose to brain
University of Rochester Medical Center scientists showed that when rats breathe in nano-sized materials they follow a rapid and efficient pathway from the nasal cavity to several regions of the brain
This Consultative Document sets out the Health and Safety Commission’s (HSC’s) proposals for establishing Workplace Exposure Limits (WELs) for the 33 substances listed in the Directive.
Consultation ends: 27 September 2006